1. IEEE PPU Student Branch: The club is a branch of global IEEE, which is dedicated to advancing technological innovation and excellence for the benefit of humanity.  
2. IMechE PPU Student Chapter: The club designed to share knowledge and developments in mechanical engineering among students.
3. American Society of Civil Engineers: The club dedicated to spread the science and profession of civil engineering.
4. Tamayyaz Alumni: The club designed to empower Palestinian students and increase their competitiveness in local market.
5. Google Developer Student Club: The club is a sub of Google developer program, which is designed to attract students whose passion, are in programming.
6. Polytechnic Medical Students’ Research Association - PMRA: The club designed to spread awareness among medical students and personnel about scientific research by teaching its principles and its professional application. 
7. Polytechnic Medical Student Association “PMSA” - Hebron PPU: The club designed to provide medical students with the necessary skills and resources to become leaders in healthcare.
8. Code club: The club designed to attract students with interest in coding.
9. Accounting Club: The club designed to increase accounting awareness and knowledge between university students.
10. Choir Club:The club dedicated to gather students who love to sing. 
11. Scout Club: The club dedicated to students who love to play scout. 
12. Dabke Club: The club dedicated to students who love to play Dabke. 
13. Football Club: The club dedicated to students who love to play Football. 
14. Volleyball Club: The club dedicated to students who love to play Volleyball.
15. Basketball Club: The club dedicated to students who love to play Basketball.
16. Badminton Club: The club dedicated to students who love to play Badminton.  
17. Karate Club: The club dedicated to students who love to play Karate. 
18. Boxing Club: The club dedicated to students who love to play Boxing.
19. Chess Club: The club dedicated to students who love to play Chess.
20. Hult Prize: The club designed to enable the new generation to deliver social change through education and entrepreneurship.
21. Student Council: The club aims to serve students through students. The club members are listening and collecting student’s problems and issues then transfer them to university management for solution.